School of Pharmaceutical Sciences, Universiti Sains Malaysia

Siti Sarah Fazalul Rahiman

SITI SARAH 270917
Siti Sarah Fazalul Rahiman, Dr.
Lecturer
B. Pharm. (Hons.) (USM)
M. Sc. (UPM)
Ph. D (The University of Queensland, Australia)
J01 Room 131A
School of Pharmaceutical Sciences
Tel : 604-6533888 Ext. 2793

Email :sarahfazalul@usm.my
 

Discipline

Pharmacology

Research Interest

Immunomodulation of macrophage inflammatory pathways by natural product-derived compounds for the therapy against cancer and diseases of inflammation.

Expertise

Human macrophage model; Intracellular signaling in inflammation (TLR4 activation, NF-kappaB, cytokines release); Immunocytochemistry

Reselected Publications

  1. Rahiman SS, Morgan M, Gray P, Shaw PN, Cabot PJ. Inhibitory effects of dynorphin 3-14 on the lipopolysaccharide-induced toll-like receptor 4 signalling pathway. Peptides. 2017;90:48-54.
  2. Fazalul Rahiman SS, Morgan M, Gray P, Shaw PN, Cabot PJ. Dynorphin 1-17 and its N-terminal biotransformation fragments modulate lipopolysaccharide-stimulated nuclear factor-kappaB nuclear translocation, interleukin-1beta and tumour necrosis factor-alpha in differentiated THP-1 cells. PLoS One. 2016;11(4):e0153005.
  3. Fazalul Rahiman SS, Basir R, Talib H., Tie TH, Chuah YK, Jabbarzare M, Chong WC, Mohd Yusoff MA, Nordin N, Yam MF, Abdul Majid R. Interleukin-27 exhibited anti-inflammatory activity during Plasmodium berghei infection in mice. Tropical Biomedicine. 2013; 30(4): 663-80.
  4. Basir R, Fazalul Rahiman SS, Hasballah K, Chong WC, Talib H, Yam MF, Jabbarzare M, Tie TH, Othman F, Mohd Moklas MA, Abdullah WO, Ahmad Z. Plasmodium berghei ANKA infection in ICR mice as a model of cerebral malaria. Iranian Journal of Parasitology. 2012, 7(4): 62-74.

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School of Pharmaceutical Sciences
11800 Universiti Sains Malaysia, Pulau Pinang, Malaysia.

Tel : +604-653 2211  |  Fax: +604-657 0017