Amirah Mohd Gazzali

Discipline

Pharmaceutical Technology

Courses taught

• FAR 122/4 (Course coordinator)
• FAR 222/3
• FAR 423/4

Research Interest

• Development of targeted drug delivery system (for cancer and neglected tropical disease)
• Drug formulation

Expertise

• Development of targeted drug delivery system through click chemistry synthesis technique

• Drug formulation development (advanced and conventional delivery system)

• Analytical evaluation (i.e NMR, IR, Mass spectroscopy) of drugs, drug conjugates and formulated drug system

Consultation

NA

Selected Publication

1.0 Journal article

2017

Amirah Mohd Gazzali, Ludovic Colombeau, Habibah A. Wahab, Céline Frochot, Régis Vanderesse, Samir Acherar (2017). Synthesis of mono-, di- and triporphyrin building blocks by click chemistry for photodynamic therapy application. Tetrahedron, 73 : 532-541

2016             

Amirah Mohd Gazzali,  Mathilde Lobry, Ludovic Colombeau, Samir Acherar, Henri Azais, Serge Mordon, Philippe Arnoux, Francis Baros, Régis Vanderesse, Céline Frochot (2016). Stability of folic acid under several parameters. European Journal of Pharmaceutical Science, 93 (419-430).

Ludovic Colombeau, Samir Acherar, Francis Baros, Philippe Arnoux, Amirah Mohd Gazzali, Khalil Zaghdoudi, Megali Toussaint, Régis Vanderesse, Céline Frochot (2016). Inorganic nanoparticles for photodynamic therapy. Chapter in Light-Responsive Nanostructured Systems for Application in Nanomedicine. 370 : 113-134.

Ezatul E. Kamarulzaman, Régis Vanderesse, Amirah Mohd Gazzali, Muriel Barberi-Heyob, Cédric Boura, Céline Frochot, Omar Shawkataly, André Aubry, Habibah A Wahab (2016). Molecular modelling, synthesis and biological evaluation of peptide inhibitors as anti-angiogenic agent targeting Neuropilin-1 for anticancer application.Journal of Biomolecular Structure & Dynamics, p.1-20 

2015

Ezatul Kamarulzaman, Amirah Mohd Gazzali, Samir Acherar, Céline Frochot, Muriel Barberi, Cédric Boura, Patrick Chaimbault, Estelle Sibille, Habibah Wahab, Régis Vanderesse (2015) New Peptide-Conjugated Chlorin-Type Photosensitizer Targeting Neuropilin-1 for Anti-Vascular Targeted Photodynamic Therapy. International Journal of Molecular Sciences. 16, 24059-24080.

2014

Amirah M.G, Amirul A.A, Habibah A. Wahab (2014) Formulation and characterization of rifampicin-loaded P(3HB-co-4HB) nanoparticles. International Journal of Pharmacy and Pharmaceutical Sciences. 6(4):140-146

2.0 Presentations

i) Oral Presentations

Modification of KDKPPR peptide through Alanine-scanning technique to investigate the effect on its binding on Neuropilin-1 receptor for photodynamic therapy application Photoynamic therapy and Photodiagnosis Update (International Congress) 24-28 October 2016 (Nancy, France)

Synthesis of platforms combining porphyrin and peptides via click chemistry technique for anti-cancer photodynamic therapy Seminaire Ecole Doctoral RP2E 28 January 2016 (Vandeouvre-les-Nancy, France)

Synthesis of platforms combining porphyrin and peptides via click chemistry technique Photodynamic therapy and Photodiagnosis in Clinical Practice (International Congress) 15-18 October 2014 (Brixen, Italy)

Synthesis of platforms through click chemistry technique for peptide-assisted drug delivery in photodynamic therapy College Doctorale Franco-Allemand 03-05 (GRK 532) Seminar 12-13 June 2014, (Strasbourg, France)

Formulation and Characterization of Rifampicin-loaded P(3HB-co-4HB) nanoparticles for oral Anti-Tuberculosis Therapy 25th Scientific Meeting of Malaysian Society of Pharmacology & Physiology (MSPP) 25-26 May 2011 (Serdang, Malaysia)

ii) Poster Presentations

Synthesis of platforms combining porphyrin and peptides via click chemistry technique Photodynamic therapy and Photodiagnosis in Clinical Practice 15-18 October 2014 (Brixen, Italy)

Formulation of Nanoparticles from P(3HB-co-4HB) copolymer International Conference and Exhibition on Pharmaceutical, Nutraceutical and Cosmeceutical Technology 2010 25-26 May 2010 (Kuala Lumpur, Malaysia)

3.0 Abstract

Amirah Mohd Gazzali, Ludovic Colombeau, Samir Acherar, Bauyrzhan Myrzakhmetov, Mathilde Achard, Philippe Arnoux, Habibah A. Wahab, Céline Frochot, Régis Vanderesse. Synthesis of platforms through click chemistry technique for peptide-assisted drug delivery in photodynamic therapy of cancer. Abstract for poster presentation, 4th USM-UL Colloquium, 17-19 January 2017, Penang, Malaysia.

Eloise Thomas, Magali Toussaint, Ludovic Colombeau, Noemie Thomas-Jasniewski, Regis Vanderesse, Amirah Mohd Gazzali, Celine Frochot, Muriel Barberi-Heyob, Francois Lux, Olivier Tillement. Ultrasmall gadolinium-based nanoparticles designed for photodynamic therapy (PDT) guided by MRI. Abstract for poster presentation, Photodynamic Therapy and Photodiagnosis Update (International Congress), 24-28 October 2016, Nancy, France.

Amirah Mohd Gazzali, Cédric Boura, Thibaut Peterlini, Ludovic Colombeau, Samir Acherar, Céline Frochot, Régis Vanderesse. Modification of KDKPPR peptide through alanine-scanning technique to investigate the effect on its binding on Neuropilin-1 receptor for Photodynamic therapy application. Abstract for oral presentation, Photodynamic Therapy and Photodiagnosis Update (International Congress), 24-28 October 2016, Nancy, France.

Amirah Mohd Gazzali, Aurélie Stallivieri, Bauyrzhan Myrzakhmetov, Mathilde Achard, Philippe Arnoux, Samir Acherar, Céline Frochot, Régis Vanderesse. Synthesis of platforms combining porphyrin and peptides via click chemistry technique. Abstract for oral and poster presentations, Photodynamic Therapy and Photodiagnosis in Clinical Practice, 14-18 October 2014, Brixen, Italy.

Amirah Mohd Gazzali, Mohd Lokman Ibrahim, Amirul Al-Ashraf Abdullah, Habibah A. Wahab. Formulation and characterization of rifampicin-loaded P(3HB-co-4HB) nanoparticles for oral anti-tuberculosis therapy. Abstract for oral presentation, 25th Scientific Meeting of Malaysian Society of Pharmacology & Physiology, 25-26 May 2011, Serdang, Malaysia.

Current Research

NA